Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans
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چکیده
منابع مشابه
Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans
Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous opioids to exert its analgesic effect using [11C]diprenorphine (DPN) positron emission tomography (PET). Patients with de-afferentation pain (phantom limb pain or Anaesthesia Dolorosa (n=5)) who obtained long-lasting ...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2017
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2016.08.038